I 70, I 65 $north
326.1 mi5 hours 26 mins
| Head west on West High Street (US 27) | 800 feet | |
| Turn right onto North College Avenue (US 27) | 400 feet | |
| Turn left onto West Church Street (US 27) | 0.2 mi | |
| Continue slightly right onto College Corner Pike (US 27) | 4.9 mi | |
| Continue onto Main Street (US 27) | 0.3 mi | |
| Continue onto Liberty Avenue (US 27) | 7.2 mi | |
| Continue onto College Corner Avenue (US 27) | 0.3 mi | |
| Make a slight left onto East Seminary Street (US 27) | 0.3 mi | |
| Turn right onto South Main Street (US 27) | 14.4 mi | |
| Continue onto Chester Boulevard (US 27) | 2.7 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 70 | 60.7 mi | |
| Take the ramp towards I 465 South | 0.3 mi | |
| Keep right at the fork | 0.5 mi | |
| Merge right onto I 465 W | 18.0 mi | |
| Continue towards I 865: Chicago | 4.9 mi | |
| Merge left onto I 65 N | 132.9 mi | |
| Turn left onto East 5th Avenue (US 12) | 1.0 mi | |
| Continue onto East 4th Avenue (US 12) | 0.7 mi | |
| Turn right onto Broadway (SR 53) | 500 feet | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto Indiana Toll Road (I 90) | 14.2 mi | |
| Continue onto Chicago Skyway (I 90 W) | 7.2 mi | |
| Keep left towards I 90 Express | 0.4 mi | |
| Merge left onto Dan Ryan Expressway (I 90) | 7.2 mi | |
| Continue onto Kennedy Expressway (I 90 W) | 1.2 mi | |
| Keep right onto Kennedy Expressway (I 90 W) | 6.9 mi | |
| Keep left towards I 90 West: O'Hare Airport | 5.9 mi | |
| Continue onto Jane Addams Memorial Tollway (I 90 W) | 1.7 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90 W) | 24.9 mi | |
| Take the ramp towards Randall Road | 0.3 mi | |
| Keep right at the fork | 100 feet | |
| Go straight onto Randall Road (CR 34) | 5.5 mi | |
| Turn right onto Harnish Drive | 0.5 mi | |
| You have arrived at your destination |
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Oxford, Ohio - Algonquin, Illinois