How to get from Panacea, Florida to Sanibel, Florida

Discover, print or download the driving directions for the best route to go from Panacea, Florida to Sanibel, Florida.

Enlarge the route map Panacea, Florida - Sanibel, Florida

Driving directions from Panacea, Florida to Sanibel, Florida

US 19; US 98; US 27 Alternate, I 75 $south

388.3 mi6 hours 39 mins

Head north on Coastal Highway (US 98) 57.4 mi
Turn right onto Byron Butler Parkway (US 19) 66.6 mi
Continue onto Main Street (US 19) 59.9 mi
Turn left onto Ponce de Leon Boulevard (US 98) 4.1 mi
Keep left onto Ponce de Leon Boulevard (US 98) 11.8 mi
Turn left onto Jefferson Street (US 98) 1,000 feet
Turn right onto Mildred Avenue (US 41) 300 feet
Turn left onto Broad Street (US 41) 0.8 mi
Turn right onto Jefferson Street (US 98) 1.5 mi
Continue onto Cortez Boulevard (US 98) 4.2 mi
Turn right onto Spring Lake Highway (CR 541) 6.1 mi
Continue onto Lake Lola Road (CR 41) 1.0 mi
Keep left onto Blanton Road (CR 41) 0.5 mi
Take the ramp on the right 0.2 mi
Merge left onto I 75 S 18.6 mi
Keep left towards South I 75: Naples 16.2 mi
Continue onto I 75 S 58.3 mi
Keep left onto I 75 S 42.2 mi
Take the ramp towards Tuckers Grade 0.3 mi
Keep left at the fork 300 feet
Turn right onto Tuckers Grade (CR 762) 1.0 mi
Turn left onto Tamiami Trail (US 41) 11.4 mi
Continue onto North Cleveland Avenue (US 41) 5.5 mi
Turn right onto McGregor Boulevard 10.0 mi
Turn right to stay on McGregor Boulevard (CR 867) 4.8 mi
Continue onto Sanibel Causeway Boulevard (Span A) 2.8 mi
Continue onto Causeway Road 0.4 mi
Turn right onto Periwinkle Way 2.2 mi
Turn right onto Dunlop Road 700 feet
You have arrived at your destination

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Panacea, Florida - Sanibel, Florida

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