I 55 $north, I 70
389.3 mi6 hours 18 mins
| Head west on West Main Street (US 67 Business) | 200 feet | |
| Make a slight right to stay on West Main Street (US 67 Business) | 700 feet | |
| Turn right onto Coffman Street (US 67 Business) | 400 feet | |
| Make a slight left onto Taylor Avenue (US 67 Business) | 0.9 mi | |
| Continue onto South Desloge Drive (US 67 Business) | 2.0 mi | |
| Take the ramp on the left towards US 67 North: Saint Louis | 900 feet | |
| Merge left onto US 67 N | 26.6 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 55 N | 34.6 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep left towards I 55 North: Chicago | 0.6 mi | |
| Merge right onto I 55 N | 15.5 mi | |
| Keep right towards I 70 East: Indianapolis | 223.7 mi | |
| Keep right towards 10 Street | 2.2 mi | |
| Take the ramp towards Rural Street | 900 feet | |
| Make a slight right onto North Rural Street | 200 feet | |
| Continue onto North Keystone Avenue | 2.7 mi | |
| Turn right onto East Fall Creek Parkway North Drive | 1,000 feet | |
| Continue onto Binford Boulevard | 5.8 mi | |
| Continue onto I 69 N | 3.4 mi | |
| Keep left onto I 69 N | 21.3 mi | |
| Continue onto I 69 N | 38.6 mi | |
| Take exit 264 towards SR 18: Marion | 0.3 mi | |
| Turn right onto East North 00 South (SR 18) | 2.4 mi | |
| Turn left onto North 900 East (SR 5) | 4.4 mi | |
| You have arrived at your destination |
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Park Hills, Missouri - Van Buren, Indiana