I 80, I 84 $east
645.5 mi10 hours 45 mins
| Head northeast on Grant Street (Purple Belt) | 100 feet | |
| Make a U-turn and continue on Grant Street (Purple Belt) | 700 feet | |
| Take the ramp towards I 376 East: Monroeville | 0.4 mi | |
| Merge right onto Penn-Lincoln Parkway East (I 376 E) | 13.8 mi | |
| Merge left onto William Penn Highway (US 22 E) | 1.6 mi | |
| Keep left onto William Penn Highway (US 22 E) | 43.1 mi | |
| Continue onto Admiral Peary Highway (US 22 E) | 13.6 mi | |
| Continue onto William Penn Highway (US 22 E) | 17.2 mi | |
| Keep left towards I 99 North: Altoona | 0.9 mi | |
| Merge left onto I 99 N | 44.9 mi | |
| Keep left towards Bellefonte | 12.0 mi | |
| Continue onto US 220 | 0.4 mi | |
| Turn left onto US 220 N | 0.3 mi | |
| Continue onto I 80 | 400 feet | |
| Continue onto I 80 N | 99.0 mi | |
| Take exit 260B on the left towards I 81 North: Wilkes-Barre | 0.7 mi | |
| Merge left onto I 81 N | 34.7 mi | |
| Take the ramp towards I-84 east | 0.4 mi | |
| Keep left at the fork | 0.3 mi | |
| Keep right towards I 84 East: Mt Pocono | 0.4 mi | |
| Continue onto I 84 E | 3.4 mi | |
| Take the ramp on the left towards I 84 East: Milford | 129.0 mi | |
| Keep right towards Waterbury | 0.8 mi | |
| Keep left onto Yankee Expressway (I 84 E) | 41.7 mi | |
| Keep right onto Yankee Expressway (I 84 E) | 12.7 mi | |
| Continue onto Bulkeley Bridge (I 84 E) | 0.2 mi | |
| Continue onto Grand Army of the Republic Highway (I 84 E) | 1.3 mi | |
| Keep left onto Grand Army of the Republic Highway (I 84 E) | 0.8 mi | |
| Merge left onto Wilbur Cross Highway (I 84 E) | 40.7 mi | |
| Keep right towards I 90 East: New Hampshire | 0.4 mi | |
| Merge left onto Massachusetts Turnpike (I 90 E) | 11.2 mi | |
| Take exit 10 towards I 395: Auburn | 0.3 mi | |
| Keep left at the fork | 0.7 mi | |
| Continue onto I 290 E | 20.1 mi | |
| Keep left towards I 495 North: Lowell | 0.7 mi | |
| Merge left onto I 495 N | 22.1 mi | |
| Take exit 33 towards MA 4: North Chelmsford | 0.3 mi | |
| Turn left onto North Road (MA 4) | 1.5 mi | |
| Enter the roundabout and take the 2nd exit onto Drum Hill Rotary | 700 feet | |
| Exit the roundabout onto Drum Hill Rotary | 200 feet | |
| Take the ramp towards US 3 North: Nashua New Hampshire | 0.2 mi | |
| Merge left onto US 3 | 34.0 mi | |
| Continue onto I 93 Onramp North (I 293 N) | 0.7 mi | |
| Merge right onto Everett Turnpike (I 93 N) | 1.6 mi | |
| Keep left onto Everett Turnpike EzPass Lanes (I 93 N) | 10.2 mi | |
| Continue onto Styles Bridges Highway (I 93 N) | 18.7 mi | |
| Take exit 20 towards US 3: Laconia | 0.4 mi | |
| Keep left at the fork | 200 feet | |
| Turn left onto Laconia Road (US 3) | 4.7 mi | |
| Continue onto Daniel Webster Highway (US 3) | 1.6 mi | |
| Continue onto NH 11A | 1.2 mi | |
| Turn left onto Main Street (NH 106) | 300 feet | |
| Turn right onto Beacon Street East | 700 feet | |
| You have arrived at your destination |
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Pittsburgh, Pennsylvania - Laconia, New Hampshire