How to get from Plymouth, North Carolina to Santee, South Carolina

Discover, print or download the driving directions for the best route to go from Plymouth, North Carolina to Santee, South Carolina.

Enlarge the route map Plymouth, North Carolina - Santee, South Carolina

Driving directions from Plymouth, North Carolina to Santee, South Carolina

US 64, I 95 $south

307.8 mi4 hours 49 mins

Head southwest on East Main Street (NC 1325) 200 feet
Turn left onto Washington Street 0.6 mi
Turn right onto US Highway 64 West (US 64) 19.7 mi
Turn left onto US 13 S 1.8 mi
Continue onto US 13 S 42.1 mi
Take the ramp onto US 64 Business W 0.3 mi
Turn left onto N Raleigh Street 300 feet
Continue onto E Raleigh Boulevard (US 64 Business) 2.2 mi
Continue onto E Raleigh Blvd 0.3 mi
Continue onto W Raleigh Boulevard (NC 97) 13.1 mi
Take the ramp on the left towards NC 97: Airport 0.3 mi
Merge left onto I 95 S 226.9 mi
Take the ramp towards SC 6: Santee 0.2 mi
Keep right towards SC 6 West: Santee 200 feet
Make a slight right onto Old Number Six Highway (SC 6) 0.2 mi
Turn left onto Bass Drive 400 feet
You have arrived at your destination

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Plymouth, North Carolina - Santee, South Carolina

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