I 75 $south, Ohio Turnpike
206.7 mi3 hours 32 mins
| Head west on Township Road D | 1.1 mi | |
| Turn right onto Point Pelee Road (33) | 0.3 mi | |
| Make a slight right onto Mersea 12 Road | 3.2 mi | |
| Turn left onto Mersea 2 Road | 0.6 mi | |
| Continue onto Oak Street | 0.7 mi | |
| Turn right onto County Road 33 (33) | 2.1 mi | |
| Continue onto Talbot Trail (3) | 14.9 mi | |
| Continue onto Kings Highway 3 (3) | 6.5 mi | |
| Continue onto Talbot Road (3) | 2.9 mi | |
| Enter the roundabout and take the 2nd exit onto Talbot Road (3) | 200 feet | |
| Exit the roundabout onto Talbot Road (3) | 2.5 mi | |
| Continue onto Huron Church Road (3) | 3.8 mi | |
| Take the ramp on the left towards Bridge to USA | 0.3 mi | |
| Continue slightly right onto Ambassador Bridge | 1.3 mi | |
| Keep left at the fork | 0.6 mi | |
| Merge left onto Fisher Freeway (I 75 S) | 13.0 mi | |
| Continue onto Detroit-Toledo Expressway (I 75 S) | 38.4 mi | |
| Take exit 208 towards I-280 South: Cleveland | 500 feet | |
| Keep left towards I-280 South: Cleveland | 0.3 mi | |
| Keep right towards I-280 South: Cleveland | 900 feet | |
| Continue onto I 280 S | 12.1 mi | |
| Take exit 1A towards I 80: Chicago | 0.6 mi | |
| Keep right at the fork | 0.5 mi | |
| Merge left onto Ohio Turnpike (I 80 E) | 69.3 mi | |
| Keep left onto Ohio Turnpike (I 80 E) | 9.2 mi | |
| Keep right onto I 480 E | 9.8 mi | |
| Take the ramp towards I 71: Cleveland | 0.7 mi | |
| Keep left at the fork | 0.3 mi | |
| Merge left onto Berea Freeway | 0.5 mi | |
| Merge right onto I 71 N | 8.5 mi | |
| Merge left onto Innerbelt (I 90) | 1.3 mi | |
| Take exit 172A towards East 9th Street | 0.3 mi | |
| Go straight onto East 9th Street | 0.9 mi | |
| You have arrived at your destination |
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Point Pelee, Ontario - Cleveland, Ohio