I 22 $east; US 78 $east, I 65 $south
318.4 mi5 hours 5 mins
| Head north on South Main Street (MS 41) | 13.7 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto I 22 E | 136.3 mi | |
| Keep right towards I 65 South: Birmingham | 0.5 mi | |
| Merge left onto I 65 S | 95.9 mi | |
| Take exit 168 towards 80 | 700 feet | |
| Keep left onto US 82 | 300 feet | |
| Turn left onto West Boulevard (US 80) | 5.5 mi | |
| Turn right onto Troy Highway (US 231) | 62.4 mi | |
| Turn left onto SR 123 | 3.7 mi | |
| You have arrived at your destination |
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Pontotoc, Mississippi - Ariton, Alabama