Queen Elizabeth Way, Simcoe Street
167.5 mi3 hours 5 mins
| Head west on Clarence Street | 100 feet | |
| Turn right onto King Street | 0.9 mi | |
| Turn right onto Main Street West (3) | 0.9 mi | |
| Turn left onto Highway 140 (140) | 6.7 mi | |
| Turn left onto East Main Street | 0.9 mi | |
| Enter the roundabout and take the 1st exit onto Highway 406 | 0 feet | |
| Exit the roundabout onto Highway 406 | 15.7 mi | |
| Keep left towards QEW: Toronto | 1.1 mi | |
| Merge left onto Queen Elizabeth Way (QEW N) | 55.0 mi | |
| Take the ramp towards 427: Pearson | 0.7 mi | |
| Continue onto Highway 427 Express (427 N) | 2.0 mi | |
| Take the ramp towards Highway 27 | 0.4 mi | |
| Merge right onto Highway 427 Collector (427) | 0.2 mi | |
| Keep left towards 427 Express | 0.4 mi | |
| Merge left onto Highway 427 (427 N) | 0.5 mi | |
| Take the ramp towards 401 East | 0.9 mi | |
| Merge left onto Highway 401 (401 E) | 1.7 mi | |
| Keep left towards 401 East | 11.7 mi | |
| Take the ramp towards 404: Newmarket | 0.6 mi | |
| Keep left towards 404: Newmarket | 0.4 mi | |
| Continue onto Highway 404 (404) | 1.6 mi | |
| Keep left onto Highway 404 (404) | 2.3 mi | |
| Take the ramp | 600 feet | |
| Merge right onto Highway 404 (404 N) | 0.5 mi | |
| Take the ramp towards 407 ETR | 0.4 mi | |
| Keep right towards 407 East: 407 ETR | 0.9 mi | |
| Merge left onto Highway 407 ETR (407 ETR E) | 24.6 mi | |
| Take the ramp towards 2 | 0.3 mi | |
| Turn left onto Simcoe Street North (2) | 20.0 mi | |
| Turn right onto Little Britain Road (4) | 13.6 mi | |
| Continue onto Angeline Street South (4) | 300 feet | |
| Turn right onto Highway 7 / 35 (7) | 0.9 mi | |
| Turn left onto Lindsay Street South (15) | 1.5 mi | |
| You have arrived at your destination, on the left |
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Port Colborne, Ontario - Lindsay, Ontario