How to get from Portland, Maine to Amherst, Massachusetts

Discover, print or download the driving directions for the best route to go from Portland, Maine to Amherst, Massachusetts.

Enlarge the route map Portland, Maine - Amherst, Massachusetts

Driving directions from Portland, Maine to Amherst, Massachusetts

Maine Turnpike, I 495 $south

175.0 mi3 hours 4 mins

Head northeast on Congress Street 900 feet
Turn left onto Franklin Street (US 1A) 0.5 mi
Keep left at the fork 0.3 mi
Merge left onto I 295 S 3.7 mi
Keep left onto I 295 S 2.7 mi
Merge left onto Maine Turnpike (I 95 S) 60.6 mi
Keep right towards I 495 South: Worcester 42.6 mi
Take exit 29B towards MA 2 West: Leominster 0.4 mi
Merge left onto Captain Isaac Davis Highway (MA 2) 1.2 mi
Continue onto Route 2 (MA 2) 3.5 mi
Continue onto Concord Turnpike (MA 2) 37.6 mi
Take exit 16 on the left towards US 202 South: Athol 0.4 mi
Turn left onto Daniel Shays Highway (US 202) 14.3 mi
Turn right onto Amherst Road 4.2 mi
Continue onto Pelham Road 0.9 mi
Continue onto Main Street 1.3 mi
Turn right onto North Pleasant Street 100 feet
Turn left onto Amity Street 0.7 mi
Turn left onto University Drive 300 feet
You have arrived at your destination

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Portland, Maine - Amherst, Massachusetts

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