I 80, PA 948
283.7 mi5 hours 25 mins
| Head north on 5th Street (US 222 Business) | 0.4 mi | |
| Make a slight left onto Centre Avenue (PA 61) | 3.0 mi | |
| Continue onto Pottsville Pike (PA 61) | 4.7 mi | |
| Continue onto Centre Avenue (PA 61) | 1.0 mi | |
| Continue onto Pottsville Pike (PA 61) | 3.2 mi | |
| Continue onto Shoemaker Avenue (PA 61) | 0.6 mi | |
| Continue onto Pottsville Pike (PA 61) | 6.7 mi | |
| Continue onto Centre Turnpike (PA 61) | 13.9 mi | |
| Continue onto South Claude A. Lord Boulevard (PA 61) | 1.5 mi | |
| Continue onto Pottsville Saint Clair Highway (PA 61) | 1.0 mi | |
| Continue onto Joseph H. Long Boulevard (PA 61) | 5.3 mi | |
| Continue onto South Lehigh Avenue (PA 61) | 0.6 mi | |
| Turn left onto West Oak Street (PA 61) | 1.2 mi | |
| Continue onto Fountain Street (PA 61) | 4.2 mi | |
| Turn right onto Broad Street (PA 61) | 0.9 mi | |
| Make a slight right onto South Hoffman Boulevard (PA 61) | 0.5 mi | |
| Turn left onto Centre Street (PA 54) | 1.4 mi | |
| Continue onto Main Street (PA 54) | 23.0 mi | |
| Turn right onto Danville-Riverside Bridge Road (PA 54) | 0.3 mi | |
| Continue onto Factory Street (PA 54) | 700 feet | |
| Continue onto Continental Boulevard (PA 54 W) | 3.0 mi | |
| Take the ramp | 0.4 mi | |
| Merge left onto I 80 | 126.7 mi | |
| Take the ramp towards US 219: DuBois | 0.5 mi | |
| Keep right towards US 219: DuBois | 400 feet | |
| Merge left onto Rich Highway (US 219) | 7.2 mi | |
| Continue onto Clark Street (US 219) | 600 feet | |
| Turn right onto Main Street (US 219) | 16.9 mi | |
| Continue onto East Main Street (US 219) | 1.0 mi | |
| Turn right onto Montmorenci Avenue (PA 948) | 1.0 mi | |
| Continue onto Montmorenci Road (PA 948) | 4.4 mi | |
| Turn left to stay on Montmorenci Road (PA 948) | 4.4 mi | |
| Continue onto Highland Road (PA 948) | 1.5 mi | |
| Go straight onto Montmorenci Road (PA 948) | 6.6 mi | |
| Keep left onto PA 66 | 800 feet | |
| Turn right | 200 feet | |
| Turn left onto PA 948 | 8.5 mi | |
| Continue onto PA 666 | 2.4 mi | |
| Turn left onto West Main Street (US 6 W) | 1.2 mi | |
| Continue onto Grand Army of the Republic Highway (US 6 W) | 4.5 mi | |
| Continue onto South Main Street (US 6 W) | 1.4 mi | |
| Continue onto Grand Army of the Republic Highway (US 6 W) | 2.9 mi | |
| Continue onto Main Street (US 6 W) | 0.2 mi | |
| Continue onto Crescent Park (US 6 W) | 1.8 mi | |
| Continue onto Warren Bypass (US 6 W) | 1.7 mi | |
| Continue onto Grand Army of the Republic Highway (US 6 W) | 6.9 mi | |
| Continue onto Youngsville Bypass (US 6 W) | 1.4 mi | |
| Continue onto Grand Army of the Republic Highway (US 6 W) | 2.5 mi | |
| Make a slight left onto PA 27 | 0.4 mi | |
| Turn right onto Dalrymple Street | 300 feet | |
| You have arrived at your destination |
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Reading, Pennsylvania - Pittsfield, Pennsylvania