How to get from Knoxville, TN, USA to Myrtle Beach, SC, USA

Discover, print or download the driving directions for the best route to go from Knoxville, TN, USA to Myrtle Beach, SC, USA.

Enlarge the route map Knoxville, TN, USA - Myrtle Beach, SC, USA

Driving directions from Knoxville, TN, USA to Myrtle Beach, SC, USA

I 40, I 26 $east

411.5 mi6 hours 51 mins

Head north on Waverly Street 700 feet
Turn right onto Western Avenue (SR 62) 2.3 mi
Take the ramp on the left 100 feet
Keep right at the fork 0.4 mi
Merge left onto I 40 33.3 mi
Keep right towards I 40 East: Asheville 76.3 mi
Take the ramp towards I 26 East: Hendersonville 13.3 mi
Continue onto I 26 E 134.0 mi
Take the ramp towards I 20 East: Florence 0.3 mi
Merge left onto I 20 79.3 mi
Turn left onto West Palmetto Street (US 76) 22.6 mi
Go straight onto SC 576 S 3.1 mi
Continue onto US 501 Business 43.0 mi
Turn right onto 3rd Avenue South 1.1 mi
Turn right onto South Kings Highway (US 17 Business) 1.4 mi
Turn right onto Harrelson Boulevard 0.3 mi
Turn left onto Radar Road 0.4 mi
Turn right 800 feet
Turn left 600 feet
You have arrived at your destination, straight ahead

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Knoxville, TN, USA - Myrtle Beach, SC, USA

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