How to get from Salem, Virginia to Charleston, South Carolina

Discover, print or download the driving directions for the best route to go from Salem, Virginia to Charleston, South Carolina.

Enlarge the route map Salem, Virginia - Charleston, South Carolina

Driving directions from Salem, Virginia to Charleston, South Carolina

I 77 $south, I 26 $east

396.0 mi6 hours 8 mins

Head east on East Main Street (US 460) 100 feet
Turn left onto Thompson Memorial Drive (VA 311) 1.6 mi
Take the ramp on the left 0.2 mi
Merge left onto I 81 S 58.2 mi
Take the ramp towards I 77 South: Charlotte NC 0.4 mi
Continue towards I 77 South: Charlotte NC 0.4 mi
Continue onto I 77 S 100.6 mi
Keep right onto I 77 S 109.4 mi
Keep left onto I 77 S 18.4 mi
Keep left towards I 26 South: Charleston 0.8 mi
Merge right onto I 26 E 104.3 mi
Take the ramp on the left towards Visitor Center 0.4 mi
Turn right onto Meeting Street (US 52) 1.2 mi
You have arrived at your destination

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Salem, Virginia - Charleston, South Carolina

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