I 75 $north, I 95 $north
785.2 mi12 hours 15 mins
| Head south on Dunlop Road | 700 feet | |
| Turn left onto Periwinkle Way | 2.2 mi | |
| Turn left onto Causeway Road | 0.5 mi | |
| Continue onto Sanibel Causeway Boulevard (Span C) | 2.8 mi | |
| Continue onto McGregor Boulevard | 2.1 mi | |
| Continue onto Summerlin Road (CR 869) | 2.9 mi | |
| Keep right onto Summerlin Road (CR 869) | 3.1 mi | |
| Turn right onto Gladiolus Drive (CR 865) | 1.5 mi | |
| Continue onto Ben C Pratt Six Mile Cypress Parkway (FL 865) | 2.9 mi | |
| Turn right onto Daniels Parkway (CR 876) | 2.8 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 75 N | 226.0 mi | |
| Take the ramp towards FL 326 | 0.2 mi | |
| Make a slight right | 100 feet | |
| Merge left onto FL 326 | 2.6 mi | |
| Turn left onto US 301 | 5.5 mi | |
| Keep right towards North US 301: Starke | 48.4 mi | |
| Go straight onto US 301 | 21.7 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 10 E | 12.6 mi | |
| Take the ramp towards I-295: Daytona Beach | 0.2 mi | |
| Keep left towards I-295: Daytona Beach | 0.6 mi | |
| Merge left onto I 295 N | 14.2 mi | |
| Take the ramp on the left towards I 95 North: International Airport | 0.5 mi | |
| Merge left onto I 95 N | 164.9 mi | |
| Keep left towards I 95 North: Florence | 53.1 mi | |
| Take the ramp towards I 26 West: Columbia | 0.4 mi | |
| Merge left onto I 26 W | 52.2 mi | |
| Take the ramp towards I 77 North: Charlotte | 1.0 mi | |
| Merge left onto Southeastern Beltway (I 77 N) | 103.2 mi | |
| Take the ramp towards I 85 North: Greensboro | 0.4 mi | |
| Keep left towards I 85 North: Greensboro | 0.4 mi | |
| Merge left onto I 85 N | 43.7 mi | |
| Continue onto I 85 | 0.6 mi | |
| Continue onto I 85 N | 3.8 mi | |
| Keep right towards I 285 North: Lexington | 4.1 mi | |
| Keep right onto I 85 Business N | 1.9 mi | |
| Continue onto I 85 Business N | 0.6 mi | |
| Take the ramp | 0.2 mi | |
| Turn right onto Winston Road (NC 8) | 200 feet | |
| Continue onto Salem Street (NC 8) | 600 feet | |
| Make a slight left onto West 5th Street (NC 8) | 0.4 mi | |
| Turn right onto North Main Street | 700 feet | |
| You have arrived at your destination |
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Sanibel, Florida - Lexington, North Carolina