I 77 $south, I 85 $south
835.5 mi13 hours 36 mins
| Head southeast on 4th Street (US 340) | 0.4 mi | |
| Continue onto 3rd Street (US 340) | 600 feet | |
| Continue onto South Third Street (US 340) | 0.3 mi | |
| Continue onto South 3rd Street (US 340) | 4.3 mi | |
| Continue onto North Stuart Avenue (US 340) | 0.8 mi | |
| Take the ramp on the right | 900 feet | |
| Merge left onto Spotswood Trail (US 33) | 11.5 mi | |
| Turn left onto Cross Keys Road (VA 276) | 7.6 mi | |
| Continue onto Keezletown Road (VA 276) | 1.8 mi | |
| Turn right onto Weyers Cave Road (VA 256) | 1.3 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 81 S | 153.4 mi | |
| Take the ramp towards I 77 South: Charlotte NC | 0.4 mi | |
| Continue towards I 77 South: Charlotte NC | 0.4 mi | |
| Continue onto I 77 S | 100.6 mi | |
| Keep right onto I 77 S | 16.7 mi | |
| Take the ramp towards I 485 OUTER: Pineville | 0.3 mi | |
| Keep right at the fork | 0.9 mi | |
| Merge left onto I 485 | 10.3 mi | |
| Take the ramp towards I 85: Spartanburg | 0.4 mi | |
| Keep right towards I 85 South: Spartanburg | 0.9 mi | |
| Merge left onto I 85 S | 236.0 mi | |
| Continue onto James Wendell George Parkway (I 75 S) | 2.3 mi | |
| Keep right towards I 85 South: Airport Domestic | 55.6 mi | |
| Take the ramp towards I 185 South: Columbus | 39.9 mi | |
| Take the ramp towards GA 22: Macon | 0.3 mi | |
| Keep right towards GA 22 West: Phenix City | 0.8 mi | |
| Merge left onto US 80 W | 5.6 mi | |
| Turn left onto US 80 | 2.8 mi | |
| Take the ramp onto US 431 | 700 feet | |
| Keep right onto US 431 | 200 feet | |
| Merge left onto Martin Luther King Jr Parkway North (US 431) | 2.8 mi | |
| Continue onto Old Seal Highway (US 431) | 42.6 mi | |
| Continue onto South Eufaula Avenue (US 431) | 9.6 mi | |
| Continue onto S Eufaula Ave (US 431) | 0.9 mi | |
| Continue onto South Eufaula Avenue (US 431) | 39.8 mi | |
| Keep left at the fork | 100 feet | |
| Turn left onto Montgomery Highway (US 231 Business) | 200 feet | |
| Continue onto North Oates Street (US 231 Business) | 82.1 mi | |
| Turn left onto Harrison Avenue (US 231) | 1.1 mi | |
| You have arrived at your destination |
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Shenandoah, Virginia - Panama City, Florida