I 10; US 70 $east, I 25 $north
498.4 mi8 hours 14 mins
| Head north on North Lenzner Avenue | 0 feet | |
| Turn left onto East Fry Boulevard | 1.4 mi | |
| Turn right onto Buffalo Soldier Trail | 1.5 mi | |
| Continue onto State Route 90 (AZ 90) | 3.0 mi | |
| Continue onto South Huachuca Boulevard (AZ 90) | 2.2 mi | |
| Continue onto State Route 90 (AZ 90) | 22.2 mi | |
| Take the ramp towards I 10 | 0.4 mi | |
| Merge left onto I 10 E | 171.3 mi | |
| Take the ramp towards Cedar Street | 1,000 feet | |
| Go straight onto East Cedar Street (US 180) | 600 feet | |
| Turn left onto North Pearl Street | 400 feet | |
| Turn left | 0.3 mi | |
| Continue onto US 180 | 500 feet | |
| Turn right onto North Gold Avenue (US 180) | 1.2 mi | |
| Turn right onto Hatch Highway (NM 26) | 6.7 mi | |
| Continue onto New Mexico State Road 26 (NM 26) | 39.4 mi | |
| Continue onto West Hall Street (NM 26) | 0.4 mi | |
| Turn left onto Franklin Street (NM 26) | 0.7 mi | |
| Continue onto New Mexico State Road 26 (NM 26) | 0.7 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 25 N | 240.8 mi | |
| Take the ramp towards US 84 | 0.2 mi | |
| Keep left towards US 84: Los Alamos | 0.8 mi | |
| Continue onto South Saint Francis Drive (US 84) | 3.4 mi | |
| Continue onto North Saint Francis Drive (US 84) | 700 feet | |
| Turn right onto Paseo de Peralta (NM 475) | 0.9 mi | |
| You have arrived at your destination |
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Sierra Vista, Arizona - Santa Fe, New Mexico