How to get from Sikeston, Missouri to Hopkinsville, Kentucky

Discover, print or download the driving directions for the best route to go from Sikeston, Missouri to Hopkinsville, Kentucky.

Enlarge the route map Sikeston, Missouri - Hopkinsville, Kentucky

Driving directions from Sikeston, Missouri to Hopkinsville, Kentucky

I 24 $east, I 24 $east; I 69 $north

141.5 mi2 hours 27 mins

Head east on Tanner Street 0 feet
Turn right onto North Prairie Avenue 0.3 mi
Turn left onto East Malone Avenue (US 60 Business) 2.9 mi
Take the ramp on the right 0.3 mi
Merge left onto I 55 S 1.1 mi
Take the ramp towards I 57 North: Chicago 0.2 mi
Merge left onto Interstate 57 (I 57 N) 23.5 mi
Take the ramp towards US 51 south: Cairo 200 feet
Continue straight 0.5 mi
Turn left onto US 51 9.7 mi
Turn left onto 4th Street (US 60) 0.2 mi
Continue onto Lee Street (US 60) 700 feet
Continue onto North 6th Street (US 60) 5.9 mi
Continue onto South 4th Street (US 60) 0.2 mi
Turn right onto Broadway (US 60) 0.6 mi
Continue onto Paducah Road (US 60) 3.2 mi
Continue onto West Kentucky Avenue (US 60) 0.5 mi
Continue onto Paducah Rd (US 60) 6.1 mi
Continue onto Old Hinkleville Rd (US 60) 10.6 mi
Take the ramp towards Nashville 0.2 mi
Merge left onto Interstate 24 (I 24 E) 60.5 mi
Take exit 65 towards US 68: Cadiz 0.3 mi
Turn left onto Hopkinsville Road (US 68) 3.8 mi
Continue onto Cadiz Road (US 68) 9.2 mi
Continue onto West 7th Street (US 68) 1.3 mi
Go straight onto West 9th Street (US 68) 0.3 mi
You have arrived at your destination

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Sikeston, Missouri - Hopkinsville, Kentucky

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