How to get from Sioux Falls, South Dakota to Macon, Missouri

Discover, print or download the driving directions for the best route to go from Sioux Falls, South Dakota to Macon, Missouri.

Enlarge the route map Sioux Falls, South Dakota - Macon, Missouri

Driving directions from Sioux Falls, South Dakota to Macon, Missouri

I 29 $south, US 36 $east; MO 110

438.9 mi6 hours 53 mins

Head south on South Minnesota Avenue (I 229 Business S) 2.4 mi
Take the ramp on the right onto I 229 Business 0.2 mi
Merge left onto I 229 S 4.2 mi
Merge left onto I 29 S 177.8 mi
Keep right towards I 29 South: Kansas City 127.0 mi
Take exit 46A towards US 36 East: Cameron 0.2 mi
Merge left onto US 36 E 126.0 mi
Take the ramp towards US 63: Macon 900 feet
Turn right onto North Missouri Street (US 63) 1.0 mi
You have arrived at your destination

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Sioux Falls, South Dakota - Macon, Missouri

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