US 20 $east, I 74 $east
750.4 mi11 hours 24 mins
| Head south on South Minnesota Avenue (I 229 Business S) | 2.4 mi | |
| Take the ramp on the right onto I 229 Business | 0.2 mi | |
| Merge left onto I 229 S | 4.2 mi | |
| Merge left onto I 29 S | 78.4 mi | |
| Take the ramp towards Downtown | 0.3 mi | |
| Turn left onto South Virginia Street (US 20 Business) | 700 feet | |
| Turn right onto Gordon Drive (US 20 Business E) | 24.6 mi | |
| Continue onto US 20 E | 193.2 mi | |
| Take the ramp towards I 380 South: Cedar Rapids | 49.2 mi | |
| Continue onto I 380 S | 16.1 mi | |
| Take the ramp towards I 80 East: Iowa City | 0.3 mi | |
| Merge left onto I 80 | 182.9 mi | |
| Continue onto I 74 E | 7.5 mi | |
| Keep right towards I 55 South | 6.4 mi | |
| Keep left towards I 74 East: Indianapolis | 80.8 mi | |
| Take the ramp towards US 150 | 1,000 feet | |
| Keep left towards US 150 West | 1,000 feet | |
| Keep left towards I 74 East | 0.3 mi | |
| Merge left onto I 74 E | 85.4 mi | |
| Continue onto I 74 | 0.4 mi | |
| Continue onto I 74 E | 6.0 mi | |
| Take the ramp towards US 31 South: East Street | 0.4 mi | |
| Merge left onto South East Street (US 31) | 10.9 mi | |
| Turn right onto Whiteland Road | 100 feet | |
| You have arrived at your destination |
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Sioux Falls, South Dakota - Whiteland, Indiana