Ohio Turnpike, Indiana Toll Road
356.4 mi5 hours 27 mins
| Head northwest on Bainbridge Road | 200 feet | |
| Continue slightly right onto S.O.M. Center Road (SR 91) | 0.5 mi | |
| Take the ramp on the right towards US 422 West: Cleveland | 0.3 mi | |
| Merge left onto US 422 W | 5.1 mi | |
| Merge left onto I-480N | 25.6 mi | |
| Keep right onto I 480 W | 1.2 mi | |
| Merge left onto Ohio Turnpike (I 80 W) | 151.1 mi | |
| Continue onto Indiana Toll Road (I 80) | 156.6 mi | |
| Continue onto Chicago Skyway (I 90 W) | 7.2 mi | |
| Keep left towards I 90 Express | 0.4 mi | |
| Merge left onto Dan Ryan Expressway (I 90) | 7.2 mi | |
| Continue onto Kennedy Expressway (I 90 W) | 0.3 mi | |
| Take the ramp towards Washington Boulevard East (100 North) | 900 feet | |
| Turn right onto West Washington Street | 0.7 mi | |
| Turn left onto North LaSalle Street | 400 feet | |
| You have arrived at your destination |
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Solon, Ohio - Chicago, Illinois