How to get from Springfield, Missouri to Greenville, Mississippi

Discover, print or download the driving directions for the best route to go from Springfield, Missouri to Greenville, Mississippi.

Enlarge the route map Springfield, Missouri - Greenville, Mississippi

Driving directions from Springfield, Missouri to Greenville, Mississippi

US 65 $south, US 65

359.6 mi6 hours 58 mins

Head east on Park Central East 500 feet
Continue onto East Saint Louis Avenue 0.8 mi
Turn left onto North National Avenue 400 feet
Turn right onto East Trafficway Street 1.2 mi
Go straight onto East Chestnut Expressway (US 65 Business) 1.5 mi
Take the ramp towards US 65 South 0.3 mi
Merge left onto Schoolcraft Freeway (US 65 S) 66.8 mi
Continue onto US 62 4.4 mi
Turn left onto Arkmo Drive (US 62) 69.4 mi
Continue onto US 65 38.1 mi
Take the ramp on the left onto US 65 S 28.0 mi
Take the ramp onto US 65 S 4.7 mi
Keep left onto I 530 S 35.0 mi
Take the ramp onto US 65B S 8.7 mi
Keep right onto US 65B 900 feet
Keep left onto US 65B 0.6 mi
Merge left onto I 530 S 200 feet
Continue onto US 65 99.5 mi
Turn right onto Martin Luther King Junior Boulevard (MS 1) 600 feet
Make a U-turn and continue on Martin Luther King Junior Boulevard (MS 1) 500 feet
You have arrived at your destination, on the left

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Springfield, Missouri - Greenville, Mississippi

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