I 77 $south, West Virginia Turnpike
601.9 mi9 hours 43 mins
| Head west on East Main Street (US 40) | 0.7 mi | |
| Continue onto National Road West (US 40) | 0.7 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto I 70 | 35.1 mi | |
| Take exit 180A towards I 77 South: Marietta | 0.5 mi | |
| Merge right onto I 77 S | 257.3 mi | |
| Keep left towards I 77 South: Roanoke | 8.7 mi | |
| Take the ramp towards I 77 South: Charlotte NC | 101.2 mi | |
| Keep right onto I 77 S | 25.4 mi | |
| Take the ramp towards I 277 South: Downtown Charlotte | 0.3 mi | |
| Keep left towards I 277 South: Downtown Charlotte | 0.4 mi | |
| Merge right onto John Belk Freeway West (I 277 S) | 1.7 mi | |
| Take the ramp on the left towards US 74 East: Independence Boulevard | 0.4 mi | |
| Continue onto East Independence Boulevard (US 74 E) | 3.3 mi | |
| Keep right onto East Independence Boulevard (US 74) | 4.7 mi | |
| Continue onto Independence Boulevard (US 74) | 4.5 mi | |
| Keep right towards US 74 East: Indian Trail | 5.6 mi | |
| Continue onto West Roosevelt Boulevard (US 74) | 6.9 mi | |
| Turn right onto Pageland Highway (US 601) | 14.7 mi | |
| Continue onto Van Lingle Mungo Boulevard (SC 151) | 1.2 mi | |
| Continue onto State Highway 151 (SC 151) | 7.2 mi | |
| Continue onto State Hwy 151 Bypass (SC 151 Bypass) | 18.2 mi | |
| Continue onto State Highway 151 (SC 151) | 5.2 mi | |
| Continue onto West Bobo Newsome Highway (SC 151) | 15.1 mi | |
| Continue onto Harry Byrd Highway (SC 34) | 4.7 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto South Governor Williams Highway (US 52) | 5.5 mi | |
| Continue onto West Lucas Street (US 52) | 4.6 mi | |
| Continue onto South Church Street | 600 feet | |
| Turn left onto East Cheves Street | 0.9 mi | |
| Turn left onto East Palmetto Street (US 76) | 18.9 mi | |
| Go straight onto SC 576 S | 3.1 mi | |
| Continue onto US 501 Business | 44.0 mi | |
| Make a slight right onto 8th Avenue North | 200 feet | |
| Turn right onto North Kings Highway (US 17 Business) | 0.3 mi | |
| Turn left onto 5th Avenue North | 0.2 mi | |
| You have arrived at your destination |
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St. Clairsville, Ohio - Myrtle Beach, South Carolina