I 70 $west; US 40 $west, I 29 $north
675.7 mi9 hours 53 mins
| Head west on Market Street | 500 feet | |
| Turn left onto South 14th Street | 800 feet | |
| Take the ramp on the left towards I 64 West | 0.3 mi | |
| Merge left onto I 64 W | 39.3 mi | |
| Take exit 1A on the left towards I 70 West: I 70 West | 92.3 mi | |
| Continue onto I 70 W | 114.9 mi | |
| Keep right towards I 70 West: Saint Joseph | 0.8 mi | |
| Keep right towards I 29 North: Saint Joseph | 4.6 mi | |
| Keep left towards I 29 North: K.C.I. Airport | 14.2 mi | |
| Merge left onto I 29 N | 2.7 mi | |
| Keep left towards I 29 North: Saint Joseph | 37.2 mi | |
| Continue onto I 29 N | 119.5 mi | |
| Take the ramp towards Downtown | 0.3 mi | |
| Turn left onto South Expressway | 1.5 mi | |
| Continue onto South 6th Street | 0.4 mi | |
| Turn left onto West Broadway | 200 feet | |
| Keep right onto West Broadway | 300 feet | |
| Turn left onto West Broadway | 0.7 mi | |
| Turn right onto North 16th Street | 1.4 mi | |
| Take the ramp | 0.5 mi | |
| Merge left onto I 29 N | 179.0 mi | |
| Take the ramp towards I 90 West: Rapid City | 0.3 mi | |
| Merge left onto Purple Heart Memorial Highway (I 90) | 64.0 mi | |
| Take the ramp towards Mitchell | 0.3 mi | |
| Turn right to stay on South Burr Street (I 90 Business) | 0.3 mi | |
| Turn left onto East Norway Avenue | 0 feet | |
| Turn right onto South Burr Street (I 90 Business) | 0.5 mi | |
| Turn left onto East Havens Avenue (I 90 Business) | 0.3 mi | |
| Continue onto West Havens Street (I 90 Business) | 900 feet | |
| You have arrived at your destination |
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St Louis, Missouri - Mitchell, South Dakota