How to get from St Louis, Missouri to Cape Girardeau, Missouri

Discover, print or download the driving directions for the best route to go from St Louis, Missouri to Cape Girardeau, Missouri.

Enlarge the route map St Louis, Missouri - Cape Girardeau, Missouri

Driving directions from St Louis, Missouri to Cape Girardeau, Missouri

I 55 $south, Interstate 55

115.1 mi1 hour 45 mins

Head east on Market Street 400 feet
Turn right onto South Tucker Boulevard 1.3 mi
Go straight onto Gravois Avenue 0.3 mi
Take the ramp on the left 800 feet
Merge left onto I 55 S 111.0 mi
Take exit 96 towards MO K: Cape Girardeau 0.2 mi
Turn left onto William Street (MO K) 2.1 mi
You have arrived at your destination

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St Louis, Missouri - Cape Girardeau, Missouri

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