I 75 $north, US 129; GA 11
340.6 mi6 hours
| Head north on 34th Street South (US 19) | 0.4 mi | |
| Turn right onto 5th Avenue North (FL 595) | 1.2 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 275 N | 37.8 mi | |
| Merge left onto I 75 N | 177.8 mi | |
| Take the ramp towards US 129 | 1,000 feet | |
| Turn left onto US 129 | 5.0 mi | |
| Turn left onto Hatley Street (US 41) | 1.0 mi | |
| Keep right onto US 129 | 37.8 mi | |
| Turn left onto US 129 | 0.3 mi | |
| Turn right onto US 221 | 12.8 mi | |
| Continue onto US 221 | 5.8 mi | |
| Turn left onto South Main Street (US 221) | 15.4 mi | |
| Continue onto South Madison Avenue (US 441) | 1.3 mi | |
| Turn right onto East Ashley Street (GA 32) | 1.0 mi | |
| Continue onto Westgreen Road (GA 32) | 2.1 mi | |
| Continue onto US 221 | 26.9 mi | |
| Turn right onto East Jefferson Street (US 221) | 600 feet | |
| Turn left onto South Cromartie Street (US 221) | 0.7 mi | |
| Continue onto East Plum Street (US 221) | 500 feet | |
| Turn left onto East Jarman Street (US 23) | 400 feet | |
| Continue onto West Coffee Street (US 23) | 800 feet | |
| Make a slight right onto North Tallahassee Street (US 221) | 0.8 mi | |
| Continue onto Uvalda Highway (US 221) | 10.7 mi | |
| Turn left onto Charlotteville Road | 0.7 mi | |
| You have arrived at your destination |
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St. Petersburg, Florida - Charlotteville, Georgia