US 45 Alternate, US 45
152.9 mi2 hours 43 mins
| Head east on Martin Luther King Jr Drive East (MS 182) | 1.4 mi | |
| Continue onto Old Highway 82 East (MS 182) | 1.6 mi | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto US 82 E | 6.3 mi | |
| Take the ramp towards US 45A: West Point | 0.3 mi | |
| Merge left onto US 45 Alternate | 56.1 mi | |
| Keep right onto US 45 N | 23.1 mi | |
| Continue onto US 45 | 41.4 mi | |
| Turn left onto Marcus J Wright Memorial (US 45) | 21.7 mi | |
| Turn right onto West Main Street (TN 365) | 0.7 mi | |
| You have arrived at your destination |
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Starkville, Mississippi - Henderson, Tennessee