US 421 $north, US 421
140.2 mi2 hours 38 mins
| Head west on East Main Street (NC 770) | 200 feet | |
| Turn left onto South Henry Street | 2.1 mi | |
| Continue onto US 220 Business | 0.2 mi | |
| Take the ramp on the left | 900 feet | |
| Merge left onto US 220 S | 11.2 mi | |
| Take the ramp onto NC 68 | 3.4 mi | |
| Turn right onto Belews Creek Road (NC 65) | 1.0 mi | |
| Continue onto US 158 | 15.4 mi | |
| Take the ramp onto US 158 W | 2.4 mi | |
| Take the ramp | 900 feet | |
| Merge left onto John Gold Memorial Expressway (US 52 S) | 2.1 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 40 | 4.7 mi | |
| Take the ramp towards US 421: Winston-Salem | 1,000 feet | |
| Keep left towards US 421 North: Yadkinville | 0.7 mi | |
| Merge right onto US 421 N | 50.3 mi | |
| Continue onto US 421 | 27.6 mi | |
| Continue onto US 221 | 2.0 mi | |
| Turn left onto Highway 105 Extension (NC 105) | 0.8 mi | |
| Turn left onto Blowing Rock Road (US 221) | 500 feet | |
| Turn right onto Winklers Creek Road | 0.2 mi | |
| Turn right onto Wilson Drive | 1,000 feet | |
| Turn left onto NC 105 | 4.6 mi | |
| Turn right onto Broadstone Road | 2.9 mi | |
| Turn left onto NC 194 | 7.4 mi | |
| Turn left onto Shawneehaw Avenue South (NC 184) | 0 feet | |
| You have arrived at your destination |
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Stoneville, North Carolina - Banner Elk, North Carolina