How to get from Stroudsburg, Pennsylvania to Columbia, South Carolina

Discover, print or download the driving directions for the best route to go from Stroudsburg, Pennsylvania to Columbia, South Carolina.

Enlarge the route map Stroudsburg, Pennsylvania - Columbia, South Carolina

Driving directions from Stroudsburg, Pennsylvania to Columbia, South Carolina

I 81 $south, I 77 $south

685.2 mi10 hours 41 mins

Head west on Main Street (US 209 Business) 1.0 mi
Take the ramp on the right 0.3 mi
Merge right onto I 80 300 feet
Keep right towards US 209 south to PA 33 south: Snydersville 21.3 mi
Continue onto PA 33 S 3.8 mi
Take the ramp towards US 22 West: Bethlehem 0.6 mi
Merge left onto Lehigh Valley Thruway (US 22 W) 17.0 mi
Merge left onto William Penn Highway (I 78 W) 43.1 mi
Continue onto 78th Division Highway (I 78 W) 7.6 mi
Continue towards I 81 South: Harrisburg 0.7 mi
Merge left onto I 81 S 369.1 mi
Take the ramp towards I 77 South: Charlotte NC 0.4 mi
Continue towards I 77 South: Charlotte NC 0.4 mi
Continue onto I 77 S 100.6 mi
Keep right onto I 77 S 109.4 mi
Keep right onto SC 277 S 8.0 mi
Turn right onto Elmwood Avenue (US 76 W) 0.9 mi
Take the ramp on the left onto US 21 S 0.3 mi
Continue onto Huger Street (US 21) 0.6 mi
Make a U-turn and continue on Huger Street (US 21) 100 feet
You have arrived at your destination, on the left

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Stroudsburg, Pennsylvania - Columbia, South Carolina

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