How to get from Sumter, South Carolina to Knoxville, Tennessee

Discover, print or download the driving directions for the best route to go from Sumter, South Carolina to Knoxville, Tennessee.

Enlarge the route map Sumter, South Carolina - Knoxville, Tennessee

Driving directions from Sumter, South Carolina to Knoxville, Tennessee

I 26 $west, I 40

306.8 mi5 hours 2 mins

Head west on West Calhoun Street (US 401) 300 feet
Turn right onto North Washington Street (US 521) 900 feet
Continue onto Broad Street (US 521) 2.9 mi
Keep left onto Broad Street (US 76 Business) 0.4 mi
Continue onto US 76 37.4 mi
Make a slight right onto Millwood Avenue (US 76) 1.4 mi
Turn left onto Gervais Street (US 1) 0.9 mi
Turn right onto Bull Street (US 76 W) 0.9 mi
Turn left onto Elmwood Avenue (US 76 W) 4.7 mi
Merge left onto I 26 W 134.4 mi
Continue onto I 26 W 12.7 mi
Take the ramp on the left towards I 40 West: Canton 108.5 mi
Take exit 388A towards SR 158 West: Downtown 0.3 mi
Keep right at the fork 400 feet
Keep left at the fork 400 feet
Turn left onto Hall of Fame Drive 0.6 mi
Turn right onto US 11 0.5 mi
Make a slight right to stay on West 5th Avenue (US 11) 200 feet
Turn left onto North Broadway (US 11) 0.5 mi
Continue onto Henley Street (US 11) 0.3 mi
You have arrived at your destination

Print directions
Sumter, South Carolina - Knoxville, Tennessee

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.