US 49W, US 49
100.9 mi1 hour 51 mins
| Head east on Quiver Street | 200 feet | |
| Turn right onto Martin L King Street | 700 feet | |
| Continue onto South Martin Luther King Jr Avenue | 0.3 mi | |
| Turn right onto US 49W | 54.4 mi | |
| Keep right onto US 49W | 0.5 mi | |
| Merge right onto Jerry Clower Boulevard (US 49) | 2.8 mi | |
| Make a slight right onto Jerry Clower Blvd N (US 49) | 36.1 mi | |
| Continue onto Medgar Evers Boulevard | 3.4 mi | |
| Take the ramp on the left | 100 feet | |
| Merge right onto West Woodrow Wilson Avenue | 1.2 mi | |
| Turn right onto North State Street (US 51) | 2.0 mi | |
| You have arrived at your destination |
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Sunflower, Mississippi - Jackson, Mississippi