How to get from Tampa, Florida to Fort Myers, Florida

Discover, print or download the driving directions for the best route to go from Tampa, Florida to Fort Myers, Florida.

Enlarge the route map Tampa, Florida - Fort Myers, Florida

Driving directions from Tampa, Florida to Fort Myers, Florida

Lee Roy Selmon Crosstown Expressway, I 75 $south

125.9 mi1 hour 57 mins

Head northwest on North Ashley Drive 800 feet
Turn right onto East Twiggs Street 0.6 mi
Turn right onto Nebraska Avenue (FL 45) 300 feet
Take the ramp on the left 800 feet
Merge left onto Lee Roy Selmon Crosstown Expressway (FL 618 Toll E) 7.8 mi
Keep right towards I 75 South: Naples 0.5 mi
Merge left onto I 75 S 55.9 mi
Keep left onto I 75 S 42.2 mi
Take the ramp towards Tuckers Grade 0.3 mi
Keep left at the fork 300 feet
Turn right onto Tuckers Grade (CR 762) 1.0 mi
Turn left onto Tamiami Trail (US 41) 11.4 mi
Make a slight left to stay on North Tamiami Trail (US 41 Business) 4.2 mi
Continue onto Edison Bridge South (US 41 Business) 1.0 mi
Continue onto Fowler Street (US 41 Business) 800 feet
Turn right onto Second Street 0.3 mi
Turn left onto Hendry Street 700 feet
Turn right onto Dr Martin Luther King Boulevard (FL 82) 100 feet
You have arrived at your destination

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Tampa, Florida - Fort Myers, Florida

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