How to get from Tampa, Florida to South Carolina

Discover, print or download the driving directions for the best route to go from Tampa, Florida to South Carolina.

Enlarge the route map Tampa, Florida - South Carolina

Driving directions from Tampa, Florida to South Carolina

I 75 $north, I 95 $north

491.0 mi7 hours 50 mins

Head northwest on North Ashley Drive 0.4 mi
Take the ramp 0.2 mi
Keep right at the fork 800 feet
Merge left onto I 275 N 17.0 mi
Merge left onto I 75 N 82.5 mi
Take the ramp towards FL 326 0.2 mi
Make a slight right 100 feet
Merge left onto FL 326 2.6 mi
Turn left onto US 301 5.5 mi
Keep right towards North US 301: Starke 48.4 mi
Go straight onto US 301 21.7 mi
Take the ramp on the left 0.2 mi
Merge left onto I 10 E 12.6 mi
Take the ramp towards I-295: Daytona Beach 0.2 mi
Keep left towards I-295: Daytona Beach 0.6 mi
Merge left onto I 295 N 14.2 mi
Take the ramp on the left towards I 95 North: International Airport 0.5 mi
Merge left onto I 95 N 164.9 mi
Keep left towards I 95 North: Florence 53.1 mi
Take the ramp towards I 26 West: Columbia 0.4 mi
Merge left onto I 26 W 52.2 mi
Take the ramp towards I 77 North: Charlotte 1.0 mi
Merge left onto Southeastern Beltway (I 77 N) 4.2 mi
Take the ramp towards SC 48: Bluff Road 0.3 mi
Turn right onto Bluff Road (SC 48) 5.4 mi
Turn left 300 feet
Turn left onto Coley Road 300 feet
Turn right onto Pincushion Road 1.6 mi
Turn right onto Back Swamp Road 0.6 mi
You have arrived at your destination

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Tampa, Florida - South Carolina

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