I 55 $north, I 29 $north
1,209.9 mi18 hours 11 mins
| Head west on West Main Street | 0.4 mi | |
| Turn right onto North Gloster Street (MS 145) | 1.2 mi | |
| Take the ramp on the right towards MS 178 West | 0.2 mi | |
| Merge left onto McCullough Boulevard (MS 178 W) | 5.2 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 22 W | 88.4 mi | |
| Take the ramp towards I 240: Nashville | 600 feet | |
| Keep left towards I 240 West: Saint Louis | 0.7 mi | |
| Merge left onto I 240 W | 4.1 mi | |
| Continue onto I 55 N | 5.5 mi | |
| Take the ramp towards I 55 North: Saint Louis | 7.9 mi | |
| Keep right onto I 55 N | 159.0 mi | |
| Keep left onto I 55 N | 1.4 mi | |
| Keep left onto Interstate 55 (I 55 N) | 101.5 mi | |
| Take exit 196 towards I 270 West: Kansas City | 0.2 mi | |
| Keep left towards I 270 West: Kansas City | 0.8 mi | |
| Merge left onto I 270 N | 11.5 mi | |
| Take exit 12 towards I 64: Wentzville | 700 feet | |
| Keep left towards I 64 West: Wentzville | 0.5 mi | |
| Merge left onto I 64 W | 25.4 mi | |
| Take exit 1A on the left towards I 70 West: I 70 West | 92.3 mi | |
| Continue onto I 70 W | 114.9 mi | |
| Keep right towards I 70 West: Saint Joseph | 0.8 mi | |
| Keep right towards I 29 North: Saint Joseph | 4.6 mi | |
| Keep left towards I 29 North: K.C.I. Airport | 14.2 mi | |
| Merge left onto I 29 N | 2.7 mi | |
| Keep left towards I 29 North: Saint Joseph | 37.2 mi | |
| Continue onto I 29 N | 119.5 mi | |
| Take the ramp towards Downtown | 0.3 mi | |
| Turn left onto South Expressway | 1.5 mi | |
| Continue onto South 6th Street | 0.4 mi | |
| Turn left onto West Broadway | 200 feet | |
| Keep right onto West Broadway | 300 feet | |
| Turn left onto West Broadway | 0.7 mi | |
| Turn right onto North 16th Street | 1.4 mi | |
| Take the ramp | 0.5 mi | |
| Merge left onto I 29 N | 301.9 mi | |
| Take the ramp onto Aberdeen, Milbank | 0.2 mi | |
| Turn left onto US 12 | 95.2 mi | |
| Turn right onto 363rd Avenue (SD 45) | 7.0 mi | |
| You have arrived at your destination |
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Tupelo, Mississippi - Belle, South Dakota