I 40, I 24 $west
769.5 mi12 hours 10 mins
| Head west on East South Main Street (NC 75) | 0.5 mi | |
| Continue onto Waxhaw Highway (NC 75) | 3.7 mi | |
| Turn right onto Charlotte Highway (US 521) | 8.4 mi | |
| Continue onto Lancaster Highway (US 521) | 1.1 mi | |
| Continue onto Johnston Road (US 521) | 2.1 mi | |
| Take the ramp | 0.2 mi | |
| Keep left at the fork | 0.7 mi | |
| Merge left onto I 485 | 14.8 mi | |
| Take the ramp towards I 85: Spartanburg | 0.2 mi | |
| Continue onto I 485 | 0.4 mi | |
| Keep left towards I 85 South: Spartanburg | 1.2 mi | |
| Merge left onto I 85 S | 19.1 mi | |
| Take the ramp towards US 74 West: Kings Mountain | 0.6 mi | |
| Merge left onto US 74 W | 89.6 mi | |
| Take the ramp on the left towards I 40 West: Canton | 129.7 mi | |
| Keep right towards Nashville | 154.6 mi | |
| Keep right towards I 24 West: Nashville | 2.1 mi | |
| Keep right towards I 24 West: Clarksville | 4.8 mi | |
| Keep left towards I 24 West: Clarksville | 112.6 mi | |
| Keep right onto I 24 W | 63.5 mi | |
| Keep left towards I 57 North: Chicago | 0.4 mi | |
| Merge left towards Mount Vernon | 51.7 mi | |
| Take the ramp on the left towards I 64 West: Saint Louis | 65.9 mi | |
| Take the ramp towards I 255 | 0.2 mi | |
| Keep right towards I 255 North: Chicago | 0.9 mi | |
| Merge left onto I 255 N | 9.6 mi | |
| Continue onto Alton Bypass (IL 255 N) | 6.8 mi | |
| Take the ramp towards IL 143: Edwardsville | 0.2 mi | |
| Keep left at the fork | 300 feet | |
| Go straight onto Edwardsville Road (IL 143) | 1.6 mi | |
| Continue onto East Madison Avenue (IL 143) | 1.7 mi | |
| Continue onto West Ferguson Avenue (IL 143) | 800 feet | |
| Continue onto Berm Highway (IL 143) | 4.2 mi | |
| Continue onto Landmarks Boulevard (US 67) | 0.5 mi | |
| Continue onto Front Street (US 67) | 0.3 mi | |
| Turn left onto West Broadway (IL 100) | 0.3 mi | |
| Continue onto Great River Road (IL 100) | 14.3 mi | |
| Go straight onto East Main Street (IL 100) | 0.5 mi | |
| You have arrived at your destination |
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Waxhaw, North Carolina - Grafton, Illinois