I 65 $north, Cumberland Parkway
270.0 mi4 hours 58 mins
| Head north on North Main Street (SR 13) | 100 feet | |
| Exit the roundabout onto Hill Street | 200 feet | |
| Go straight onto Dexter L Woods Memorial Boulevard | 1.2 mi | |
| Continue onto United States Route 64 (US 64) | 10.3 mi | |
| Turn right | 800 feet | |
| Turn right onto Natchez Trace Parkway | 21.1 mi | |
| Make a slight right towards Columbia | 0.2 mi | |
| Turn right onto Columbia Highway (US 412) | 6.5 mi | |
| Continue onto Hampshire Pike (US 412) | 13.3 mi | |
| Take the ramp onto US 412 | 0.2 mi | |
| Keep right onto US 412 | 13.9 mi | |
| Take the ramp | 900 feet | |
| Merge left onto I 65 N | 7.0 mi | |
| Keep left onto I 65 N | 29.3 mi | |
| Keep right towards Knoxville | 0.3 mi | |
| Merge left onto I 40 | 700 feet | |
| Continue towards I 24 West: Clarksville | 0.5 mi | |
| Keep left towards I 24 West: Clarksville | 0.4 mi | |
| Merge right onto I 24 W | 2.3 mi | |
| Keep right towards I 24 West: Clarksville | 2.1 mi | |
| Keep right towards I 65 North: Louisville | 7.1 mi | |
| Keep left onto I 65 N | 69.2 mi | |
| Take the ramp towards Somerset | 0.5 mi | |
| Merge left onto Cumberland Parkway (Cumberland Parkway E) | 45.9 mi | |
| Take exit 46 towards KY 61: Columbia | 0.3 mi | |
| Turn left onto KY 61 | 1.9 mi | |
| Continue onto Burkesville Street (KY 80) | 1.0 mi | |
| Enter the roundabout and take the 2nd exit onto Campbellsville Street (KY 55 Business) | 200 feet | |
| Exit the roundabout onto Campbellsville Street (KY 55 Business) | 0.5 mi | |
| Continue onto Campbellsville Road (KY 55 Business) | 7.3 mi | |
| Continue onto New Columbia Road (KY 55) | 10.3 mi | |
| Turn right onto West Broadway (US 68) | 0.8 mi | |
| Continue onto East Broadway Street (US 68) | 1.7 mi | |
| Continue onto New Lebanon Road (US 68) | 6.1 mi | |
| Continue onto New Campbellsville Road (US 68) | 5.3 mi | |
| Continue onto Campbellsville Road (US 68) | 0.5 mi | |
| Turn right onto Lovers Lane East | 1.3 mi | |
| Turn left onto New Calvary Road (KY 208) | 0.4 mi | |
| Turn left | 0.5 mi | |
| You have arrived at your destination |
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Waynesboro, Tennessee - Kentucky