I 44 $east, I 64 $east
764.1 mi12 hours 49 mins
| Head east on US 54 | 21.4 mi | |
| Turn right onto US 65 S | 13.7 mi | |
| Turn left onto MO 64 | 31.0 mi | |
| Take the ramp on the left towards I 44 East: Rolla | 0.3 mi | |
| Merge left onto I 44 E | 161.8 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep right towards I 64 East: Louisville | 70.5 mi | |
| Keep right towards I 57 South | 4.6 mi | |
| Take the ramp on the left towards I 64 East: Louisville | 257.0 mi | |
| Take exit 111 on the left towards I 64 East: Winchester | 16.6 mi | |
| Keep right towards Mountain Parkway east | 82.6 mi | |
| Continue onto Old Middle Creek Road (KY 114) | 11.3 mi | |
| Turn left | 0.3 mi | |
| Merge left onto Timberline Street (US 23) | 4.5 mi | |
| Turn right onto Bays Branch Road (KY 3) | 1.4 mi | |
| Continue onto KY 3 | 1.3 mi | |
| Turn right | 200 feet | |
| Continue onto KY 3 | 16.2 mi | |
| Turn right onto KY 645 | 1.1 mi | |
| Take the ramp | 0.2 mi | |
| Continue onto Coldwater Road (KY 908) | 0.2 mi | |
| Make a slight right | 300 feet | |
| Go straight onto Black Log Road (KY 40) | 7.6 mi | |
| Turn right onto Riverfront Road (KY 40) | 0.7 mi | |
| Turn left onto Virginia Street (KY 40) | 200 feet | |
| Continue onto Virginia Avenue | 700 feet | |
| Turn right onto Logan Street (US 52) | 6.5 mi | |
| Make a slight left onto US 52 | 4.9 mi | |
| Turn right onto US 119 N | 4.4 mi | |
| Continue onto US 119 | 13.7 mi | |
| Take the ramp | 0.7 mi | |
| Turn left onto Old US Highway 199 | 1.9 mi | |
| Continue onto WV 73 | 0.6 mi | |
| Continue onto Logan Boulevard (WV 10) | 0.3 mi | |
| Turn right to stay on Logan Boulevard (WV 10) | 0.9 mi | |
| Go straight onto WV 10 | 7.4 mi | |
| Continue onto WV 10 | 4.4 mi | |
| Turn left | 0.2 mi | |
| Turn left onto Main Street | 0.8 mi | |
| Continue onto County Highway 16 | 1.8 mi | |
| Continue onto Old Buffalo Creek Road | 0.2 mi | |
| Continue onto Main Buffalo Ck Road | 0.3 mi | |
| Continue onto County Highway 16 | 1.5 mi | |
| Continue onto Buffalo Creek Road | 6.2 mi | |
| You have arrived at your destination |
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Weaubleau, Missouri - Craneco, West Virginia