I 65 $north, I 74 $west
654.6 mi10 hours 37 mins
| Head northwest on West 4th Avenue (US 52) | 900 feet | |
| Make a sharp left | 100 feet | |
| Turn right onto Harvey Street | 0.2 mi | |
| Turn left onto US 119 | 25.2 mi | |
| Turn right onto North Mayo Trail (US 23) | 21.9 mi | |
| Take the ramp | 0.4 mi | |
| Turn left onto KY 114 | 94.1 mi | |
| Merge left onto I 64 W | 15.5 mi | |
| Keep right towards I 64 West: Louisville | 6.9 mi | |
| Keep left towards I 64 West: Frankfort | 68.3 mi | |
| Take the ramp on the left towards I 65: Nashville | 0.8 mi | |
| Keep right towards I 65 North: Indianapolis | 0.3 mi | |
| Merge left onto Abraham Lincoln Bridge (I 65) | 106.3 mi | |
| Take exit 106 towards I 465 West: Peoria | 800 feet | |
| Keep left at the fork | 0.4 mi | |
| Merge right onto I 74 W | 0.3 mi | |
| Continue onto I 74 W | 9.5 mi | |
| Continue onto I 74 | 1.5 mi | |
| Continue onto I 74 W | 3.7 mi | |
| Continue onto I 74 | 0.2 mi | |
| Continue onto I 74:I 465 W | 400 feet | |
| Keep right onto I 74 W | 165.8 mi | |
| Take the ramp towards I-74 West: Peoria | 28.4 mi | |
| Keep right towards I 74 West: Peoria | 85.6 mi | |
| Take the ramp towards I 74 West: Moline | 12.0 mi | |
| Go straight | 400 feet | |
| Turn right | 100 feet | |
| Turn left onto 19th Street (I-74 Detour) (I 74 D) | 1.4 mi | |
| Turn right onto River Dr (I-74 Detour) (I 74 D) | 600 feet | |
| Take the ramp onto I 74 D | 1.5 mi | |
| Continue onto Kimberly Road | 400 feet | |
| Go straight onto Kimberly Rd (I-74 Detour) (I 74 D) | 0.8 mi | |
| Turn left onto East Locust Street | 2.8 mi | |
| You have arrived at your destination |
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Williamson, West Virginia - Davenport, Iowa