I 40, I 74 $west
1,134.0 mi18 hours 3 mins
| Head north on South 3rd Street (US 17 Business) | 1.1 mi | |
| Continue onto Martin Luther King Jr Parkway | 4.7 mi | |
| Turn left onto North College Road (US 117) | 1.2 mi | |
| Continue onto I 40 | 115.0 mi | |
| Keep left onto Dan K Moore Freeway (I 40) | 78.5 mi | |
| Keep right onto I 40 | 20.2 mi | |
| Keep right towards I 40 Business: Kernersville | 10.8 mi | |
| Continue onto I 40 Business W | 2.0 mi | |
| Take the ramp towards US 52 North: Mount Airy - Smith Reynolds Airport | 0.3 mi | |
| Merge left onto John Gold Memorial Expressway (US 52 N) | 31.0 mi | |
| Continue towards I 74 West: Wytheville | 11.7 mi | |
| Keep right towards I 74 West: Wytheville | 13.0 mi | |
| Continue onto I 77 N | 33.1 mi | |
| Take the ramp towards I 77 North: Bluefield | 127.2 mi | |
| Keep left towards I 64 West: Huntington | 17.8 mi | |
| Take the ramp towards US 35: Winfield | 0.5 mi | |
| Keep left towards Scott Depot | 700 feet | |
| Turn right onto US 35 N | 14.1 mi | |
| Continue onto US 35 | 12.2 mi | |
| Continue onto US 35 N | 9.9 mi | |
| Continue onto US 35 W | 61.4 mi | |
| Keep left towards US 35 West: Dayton | 77.6 mi | |
| Take the ramp towards I 75 South: Cincinnati | 600 feet | |
| Keep right towards I 75 North: Toledo | 0.2 mi | |
| Merge left onto I 75 N | 0.4 mi | |
| Take exit 53 towards Second Street | 0.3 mi | |
| Turn left onto West 2nd Street | 700 feet | |
| Continue onto West 1st Street | 400 feet | |
| Continue onto Salem Avenue | 9.6 mi | |
| Take the ramp onto SR 49 N | 26.0 mi | |
| Continue onto I 70 | 72.7 mi | |
| Take the ramp towards I 65: Chicago | 0.7 mi | |
| Merge left onto I 65 N | 0.6 mi | |
| Take the ramp on the left towards Dr. Martin Luther King Jr. Street | 0.6 mi | |
| Turn right onto West 11th Street | 200 feet | |
| Continue onto Oscar Robertson Boulevard | 0.3 mi | |
| Continue onto West 10th Street | 600 feet | |
| Turn right onto Indiana Avenue | 0.7 mi | |
| Turn left onto West 16th Street | 3.0 mi | |
| Enter the roundabout and take the 1st exit onto Crawfordsville Road | 100 feet | |
| Exit the roundabout onto Crawfordsville Road | 2.1 mi | |
| Take the ramp on the right | 800 feet | |
| Keep left at the fork | 700 feet | |
| Merge right onto I 74 W | 165.5 mi | |
| Take the ramp towards I-74 West: Peoria | 28.4 mi | |
| Keep right towards I 74 West: Peoria | 51.4 mi | |
| Take the ramp towards Galesburg | 0.3 mi | |
| Go straight onto East Main Street | 1.9 mi | |
| Enter Public Square and take the 2nd exit onto West Main Street (US 150) | 500 feet | |
| Exit the roundabout onto West Main Street (US 150) | 2.1 mi | |
| Turn left | 0.4 mi | |
| Merge left onto US 34 W | 11.2 mi | |
| Continue onto US 34 | 4.8 mi | |
| Take the ramp towards US 34 West: Burlington | 53.7 mi | |
| Take the ramp towards US 218: Iowa City | 0.5 mi | |
| Merge left onto Avenue of the Saints (US 34 W) | 1.8 mi | |
| Keep right onto US 34 W | 47.5 mi | |
| Take the ramp towards US 34 | 0.5 mi | |
| Turn left onto US 34 | 0.9 mi | |
| Turn right onto Roemer Avenue (US 34 Business) | 0.2 mi | |
| Continue onto East Main Street (US 34 Business) | 1.5 mi | |
| You have arrived at your destination |
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Wilmington, North Carolina - Ottumwa, Iowa