I 75 $south, I 40; I 75 $south
280.2 mi4 hours 36 mins
| Head southwest on North Lexington Avenue (KY 29) | 100 feet | |
| Turn left onto East Main Street (KY 1268) | 0.8 mi | |
| Continue onto Glass Mill Road (KY 1268) | 1.8 mi | |
| Continue right onto Bethel Road (KY 1268) | 3.2 mi | |
| Turn right onto US 27 | 10.7 mi | |
| Merge left onto Lexington Road (US 27) | 6.8 mi | |
| Continue onto Stanford Street (US 27) | 7.0 mi | |
| Turn left onto US 150 | 15.4 mi | |
| Keep right at the fork | 6.3 mi | |
| Continue onto Crab Orchard Road (US 150) | 1.8 mi | |
| Continue onto South Daniel Boone Trail (US 25) | 2.0 mi | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto I 75 S | 112.4 mi | |
| Take the ramp towards I 75 South: Nashville | 3.5 mi | |
| Keep right towards I 75 South: Nashville | 17.1 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 72.9 mi | |
| Take the ramp towards I 24 West: Chattanooga | 0.6 mi | |
| Continue towards Chattanooga | 5.7 mi | |
| Take exit 178 towards US 27 North: Downtown | 1,000 feet | |
| Keep right at the fork | 0.2 mi | |
| Go straight onto S Market Street (SR 58) | 1.2 mi | |
| You have arrived at your destination |
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Wilmore, Kentucky - Chattanooga, Tennessee