How to get from Winston-Salem, North Carolina to Wilkesboro, North Carolina

Discover, print or download the driving directions for the best route to go from Winston-Salem, North Carolina to Wilkesboro, North Carolina.

Enlarge the route map Winston-Salem, North Carolina - Wilkesboro, North Carolina

Driving directions from Winston-Salem, North Carolina to Wilkesboro, North Carolina

I 40 Business $west; US 421 $north, US 421 $north

55.0 mi55 mins

Head north on Patterson Avenue 100 feet
Turn left onto East 5th Street 0.4 mi
Turn left onto Marshall Street North 0.4 mi
Turn right 300 feet
Take the ramp 600 feet
Merge left onto I 40 Business W 1.7 mi
Continue onto I 40 Business W 2.8 mi
Keep right towards US 421 North: Yadkinville 47.6 mi
Take the ramp towards Wilkesboro 0.2 mi
Keep left towards Wilkesboro 200 feet
Enter the roundabout and take the 2nd exit onto Oakwoods Road 100 feet
Exit the roundabout onto Oakwoods Road 1.2 mi
Turn left onto East Main Street (NC 18) 0.4 mi
You have arrived at your destination

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Winston-Salem, North Carolina - Wilkesboro, North Carolina

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