How to get from Greenville, South Carolina to Jacksonville, Florida

Discover, print or download the driving directions for the best route to go from Greenville, South Carolina to Jacksonville, Florida.

Enlarge the route map Greenville, South Carolina - Jacksonville, Florida

Driving directions from Greenville, South Carolina to Jacksonville, Florida

I 26 $east, I 95 $south

388.6 mi5 hours 59 mins

Head west on East Washington Street 0 feet
Turn right onto North Main Street 700 feet
Turn right onto East North Street 0.7 mi
Go straight onto I 385 S 10.5 mi
Keep left onto I 385 S 31.6 mi
Merge left onto I 26 E 55.8 mi
Keep right towards Charleston 60.3 mi
Take the ramp towards I 95 South: Savannah 0.9 mi
Merge left onto I 95 S 227.0 mi
Take the ramp towards Church Street 900 feet
Continue onto Cleveland Street 0.3 mi
Continue left onto West Forsyth Street 1.2 mi
Turn right onto Newnan Street 300 feet
Turn right onto East Bay Street 400 feet
You have arrived at your destination

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Greenville, South Carolina - Jacksonville, Florida

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